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KMID : 0438420110180020125
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Korean Journal of Bone Metabolism
2011 Volume.18 No. 2 p.125 ~ p.130
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The Survey of Prevalence of Osteoporosis in Alzheimer s Disease Patients
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Kim Yeob
Ahn Ki-Yong
Yoon Tae-Hyun
Lim Che-Jun
Shin Woo-Jin
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Abstract
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Objective: To evaluate the prevalence of osteoporosis in the Alzheimer s disease patients.
Methods: One hundred and twenty eight patients with Alzheimer s disease were included in this study. The patients are diagnosed with Alzheimer s disease using Korean-Mini Mental Status Examination (K-MMSE) and checked bone mineral density using single-energy (SE) quantitative computed tomography (QCT) in 2010. To define abnormality in terms of QCT of the spine, a bone mineral density (BMD) spine below 80 mg/cm3 is indicative of osteoporosis and BMD between 80 and 120 mg/cm3 is indicative osteopenia.
Results: The prevalence of osteoporosis in the control group is 29.73%. The prevalence of osteoporosis in the Alzheimer s disease patients is 96.87%. The prevalence of osteopenia in the Alzheimer’s disease patients is 3.12%. The prevalence of severe osteoporosis fracture in the Alzheimer s disease patients is 32.03%.
Conslusion: The prevalence of osteoporosis in Alzheimer’s disease patients is higher than in the control group.
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KEYWORD
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Alzheimer disease, Osteoporosis, Prevalence
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